1 Department of Medical Intensive Care, Rouen University Hospital, 76031, Rouen cedex, France.
2 Department of Biostatistics, Rouen University Hospital, 76031, Rouen cedex, France.
3 Department of Surgical Intensive Care, Rouen University Hospital, 76031, Rouen cedex, France.
4 UPRES EA 3830-IRIB, Institute for Biomedical Research, Rouen University, 76031, Rouen cedex, France.
5 Department of Medical Intensive Care, Rouen University Hospital, 76031, Rouen cedex, France. Christophe.Girault@chu-rouen.fr.
6 UPRES EA 3830-IRIB, Institute for Biomedical Research, Rouen University, 76031, Rouen cedex, France. Christophe.Girault@chu-rouen.fr.
7 Service de Réanimation Médicale, Hôpital Charles Nicolle, Centre Hospitalier Universitaire-Hôpitaux de Rouen, 1, rue de Germont, 76031, Rouen cedex, France. Christophe.Girault@chu-rouen.fr.