Generation of human haploid embryonic stem cells from parthenogenetic embryos obtained by microsurgical removal of male pronucleus

Cuiqing Zhong; Meiling Zhang; Qi Yin; Han Zhao; Yang Wang; Sexin Huang; Wenrong Tao; Keliang Wu; Zi-Jiang Chen; Jinsong Li

doi:10.1038/cr.2016.59

Generation of human haploid embryonic stem cells from parthenogenetic embryos obtained by microsurgical removal of male pronucleus

Cell Res. 2016 Jun;26(6):743-6. doi: 10.1038/cr.2016.59. Epub 2016 May 17.

Authors

Cuiqing Zhong^{1

2

3}, Meiling Zhang⁴, Qi Yin^{1

2

3}, Han Zhao⁵, Yang Wang^{4

5}, Sexin Huang⁵, Wenrong Tao⁵, Keliang Wu^{4

5}, Zi-Jiang Chen^{4

5}, Jinsong Li^{1

2}

Affiliations

¹ State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Science, Shanghai 200031, China.
² Shanghai Key Laboratory of Molecular Andrology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Science, Shanghai 200031, China.
³ College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
⁴ Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200127, China.
⁵ Center for Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, China; The Key laboratory for Reproductive Endocrinology of Ministry of Education, Jinan, Shandong 250021, China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cell Nucleus / genetics*
Embryonic Stem Cells / cytology*
Embryonic Stem Cells / metabolism*
Haploidy*
Humans
Male
Parthenogenesis / genetics*
Zygote / cytology*