Long-Term Outcomes of the Implant of a Periurethral Constrictor for Stress Urinary Incontinence Following Radical Prostatectomy

Urol Int. 2016;97(1):26-31. doi: 10.1159/000441801. Epub 2016 May 20.

Abstract

Objectives: To assess morbidity, effectiveness and quality of life (QoL) of implant of Silimed periurethral constrictor (PC) in a consecutive series of patients who had stress urinary incontinence following radical prostatectomy.

Material and methods: A prospective non-randomized study designed on patients who underwent implant of Silimed PC. Primary end point was postoperative morbidity and secondary end points were effectiveness of implant and QoL. We performed a sub-analysis of men who received previous radiation and we compared the subpopulation with radiation-naïve patients.

Results: Nineteen patients (31.6%) received pelvic radiation therapy prior implant. All procedures were completed successfully with median operative time of 55 (IQR 50-62.5) min. We recorded 47 (78.3%) postoperative complications in 30 men. Twenty-three men (38.3%) developed urethral erosion at median follow-up of 27.5 (IQR 21-35) months, and 1 man (1.9%) had rectourethral fistula at 2 months. Risk of urethral erosion increased significantly among patients who received radiation (63.1 vs. 26.8%; p < 0.001). In 12 cases (20%), we recorded malfunctioning of the reservoir requiring replacement.

Conclusion: The implant of Silimed device is not safe due to a high risk of urethral erosion. Careful patient selection and detailed counseling are mandatory when considering the implant of PC in adult patients.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Humans
  • Male
  • Prospective Studies
  • Prostatectomy / adverse effects*
  • Prostatectomy / methods
  • Prostheses and Implants*
  • Quality of Life
  • Time Factors
  • Treatment Outcome
  • Urethra / surgery*
  • Urinary Incontinence, Stress / etiology*
  • Urinary Incontinence, Stress / surgery*