Asbestos content of lung tissue in patients with malignant peritoneal mesothelioma: A study of 42 cases

Ultrastruct Pathol. 2016 May-Jun;40(3):134-41. doi: 10.3109/01913123.2016.1170085.

Abstract

Lung tissue from 42 peritoneal mesothelioma cases was analyzed by light microscopy and scanning electron microscopy/energy dispersive spectrometry. There were 34 men and 8 women with a mean age of 61 ± 10 years. Also, 17% of cases had histologically confirmed asbestosis, and 26% had only parietal pleural plaques. The asbestos body count exceeded our normal range in 22 of 42 cases (52%). Cases with asbestos-related pulmonary disease had higher fiber burdens than those without. The vast majority of fibers were commercial amphiboles (amosite with lesser amounts of crocidolite). These findings concur with previously published epidemiological observations.

Keywords: Asbestos; lung tissue; malignant peritoneal mesothelioma.

MeSH terms

  • Adult
  • Aged
  • Asbestosis / complications*
  • Asbestosis / epidemiology*
  • Female
  • Humans
  • Lung Neoplasms / complications*
  • Lung Neoplasms / pathology
  • Male
  • Mesothelioma / complications*
  • Mesothelioma / pathology
  • Mesothelioma, Malignant
  • Microscopy, Electron, Scanning
  • Middle Aged
  • Peritoneal Neoplasms / complications*
  • Peritoneal Neoplasms / pathology
  • Spectrometry, X-Ray Emission