Management of hemopoietic neoplasias during pregnancy

Crit Rev Oncol Hematol. 2016 Aug:104:52-64. doi: 10.1016/j.critrevonc.2016.05.006. Epub 2016 May 22.

Abstract

Hemopoietic neoplasias are unique cancers generally affecting bone marrow, and requires a special attention for disease control and also their complications. When these neoplastic disorders accompany to pregnancy there are many risks both for mother and foetus. Diagnostic difficulties due to the limited use of imaging modalities is essential in pregnant women. On the other hand suboptimal using of the anti-neoplastic drugs and their higher toxicity in mother and foetus must be considered in the management of these neoplastic disorders. Due to the lack of therapeutic guidelines in these cases, team approach is essential and therapy requires to the use the art of medicine.

Keywords: Chemotherapy; Fertility preservation; Hemopoietic neoplasia; Leukemia; Lymphoma; Myeloproliferative neoplasia; Pregnancy; Radiation therapy; Supportive care.

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / therapeutic use
  • Female
  • Fetus
  • Hematologic Neoplasms / epidemiology
  • Hematologic Neoplasms / etiology
  • Hematologic Neoplasms / therapy*
  • Humans
  • Neoplasm Staging
  • Pregnancy
  • Pregnancy Complications, Neoplastic / epidemiology
  • Pregnancy Complications, Neoplastic / etiology
  • Pregnancy Complications, Neoplastic / therapy*

Substances

  • Antineoplastic Agents