Genome Sequence of Vaccinia virus Strain Lister-Butantan, a Lister Vaccine Variant Used during a Smallpox Eradication Campaign in Brazil

Felipe Assis; Giliane Trindade; Betânia Drumond; Mike Frace; Scott Sammons; Ginny Emerson; Yu Li; Darin Carroll; Dhwani Batra; Jonatas Abrahão; Erna Kroon

doi:10.1128/genomeA.00536-16

Genome Sequence of Vaccinia virus Strain Lister-Butantan, a Lister Vaccine Variant Used during a Smallpox Eradication Campaign in Brazil

Genome Announc. 2016 Jun 23;4(3):e00536-16. doi: 10.1128/genomeA.00536-16.

Authors

Affiliations

¹ Laboratório de Vírus do Instituto de Ciências Biológicas da Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
² National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
³ Laboratório de Vírus do Instituto de Ciências Biológicas da Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil jonatas.abrahao@gmail.com.

Abstract

Here, we report the 187.8-kb genome sequence of Vaccinia virus Lister-Butantan, which was used in Brazil during the WHO smallpox eradication campaign. Its genome showed an average similarity of 98.18% with the original Lister isolate, highlighting the low divergence among related Vaccinia virus vaccine strains, even after several passages in animals and cell culture.