Epigenetic quality check - how good are your mesenchymal stromal cells?

Wolfgang Wagner; Joana Frobel; Roman Goetzke

doi:10.2217/epi-2016-0054

Epigenetic quality check - how good are your mesenchymal stromal cells?

Epigenomics. 2016 Jul;8(7):889-94. doi: 10.2217/epi-2016-0054. Epub 2016 Jul 1.

Authors

Wolfgang Wagner^{1

2}, Joana Frobel^{1

2}, Roman Goetzke^{1

2}

Affiliations

¹ Helmholtz-Institute for Biomedical Engineering, Stem Cell Biology & Cellular Engineering, RWTH Aachen University Medical School, Aachen, Germany.
² Institute for Biomedical Engineering - Cell Biology, University Hospital of RWTH Aachen, Aachen, Germany.

PMID: 27366986
DOI: 10.2217/epi-2016-0054

No abstract available

Keywords: DNA methylation; cellular therapy; epigenetics; heterogeneity; mesenchymal stem cells; mesenchymal stromal cells; quality control; senescence.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Clinical Trials as Topic / methods
Clinical Trials as Topic / standards
Epigenesis, Genetic / physiology*
Gene Expression Regulation
Humans
Mesenchymal Stem Cell Transplantation / standards*
Mesenchymal Stem Cells / metabolism*
Quality Control
Reproducibility of Results
Tissue Engineering / methods
Tissue Engineering / standards