Change in obsessive beliefs as predictor and mediator of symptom change during treatment of obsessive-compulsive disorder - a process-outcome study

BMC Psychiatry. 2016 Jul 7:16:220. doi: 10.1186/s12888-016-0914-6.

Abstract

Background: Cognitive models of obsessive-compulsive disorder suggest that changes in obsessive beliefs are a key mechanism of treatments for obsessive-compulsive disorder. Thus, in the present process-outcome study, we tested whether changes in obsessive beliefs during a primarily cognitive behavioral inpatient treatment predicted treatment outcome and whether these changes mediated symptom changes over the course of treatment.

Methods: Seventy-one consecutively admitted inpatients with obsessive-compulsive disorder were assessed with the Yale-Brown Obsessive-Compulsive Scale and the Obsessive Beliefs Questionnaire at treatment intake, after six weeks of treatment and at discharge, and with the Beck-Depression-Inventory-II at intake and discharge.

Results: Changes in obsessive beliefs during the first six weeks of treatment predicted obsessive-compulsive symptoms at discharge when controlling for obsessive-compulsive and depressive symptoms at intake in a hierarchical regression analysis. Multilevel mediation analyses showed that reductions in obsessive beliefs partially mediated improvements in obsessive-compulsive symptoms over time.

Conclusions: Our findings indicate that decreasing obsessive beliefs in inpatient cognitive behavioral therapy for obsessive-compulsive disorder might be a promising treatment approach.

Keywords: Change mechanism; Cognitive behavioral therapy; Inpatient treatment; Mediator; Obsessive beliefs; Obsessive-compulsive disorder.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cognitive Behavioral Therapy*
  • Culture*
  • Female
  • Humans
  • Inpatients / psychology
  • Male
  • Middle Aged
  • Obsessive-Compulsive Disorder / therapy*
  • Psychiatric Status Rating Scales
  • Treatment Outcome
  • Young Adult