Surgical Outcomes of Inferior Oblique Myectomy in Unilateral Congenital Superior Oblique Palsy with or without Trochlear Nerve

PLoS One. 2016 Jul 8;11(7):e0156872. doi: 10.1371/journal.pone.0156872. eCollection 2016.

Abstract

Objectives: To compare the surgical outcomes of inferior oblique (IO) myectomy in congenital superior oblique palsy (SOP) according to the presence of the trochlear nerve identified with high-resolution MRI.

Data extraction: Forty-one congenital SOP patients without a trochlear nerve (absent group) and 23 patients with a trochlear nerve (present group) who underwent IO myectomy as the primary surgical treatment were retrospectively reviewed. "Motor success" was defined as postoperative ipsilateral hypertropia ≤ 4 prism diopter (PD). "Head tilt improvement" was regarded as postoperative angle of head tilt < 5 degrees (°). Success rates for motor alignment and head tilt improvement, cumulative probabilities of success, and factors influencing surgical responses were evaluated.

Results: The cumulative probabilities of motor success at 2 years after IO myectomy were 92% in patients with a trochlear nerve and 86% in patients without a trochlear nerve (P = 0.138). The cumulative probabilities of undercorrection and recurrence of hypertropia after 2 years were 0% in the present group versus 21% in the absent group (P = 0.014). The cumulative probabilities of persistent head tilt after 2 years were 14% in the present group and 20% in the absent group (P = 0.486). A younger age at operation was associated with reduced probabilities of motor success and head tilt improvement (P = 0.009, P = 0.022 respectively). A greater preoperative angle of head tilt was associated with persistent head tilt after surgery (P = 0.038).

Conclusions: Congenital SOP without a trochlear nerve had a higher risk of hypertropia undercorrection after IO myectomy compared to patients with a trochlear nerve. A younger age at operation and larger preoperative head tilt was related to poor outcomes.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Magnetic Resonance Imaging*
  • Male
  • Motor Skills
  • Oculomotor Muscles / surgery*
  • Probability
  • Proportional Hazards Models
  • Recurrence
  • Retrospective Studies
  • Risk
  • Strabismus / surgery
  • Treatment Outcome
  • Trochlear Nerve / pathology
  • Trochlear Nerve / surgery*
  • Trochlear Nerve Diseases / surgery*
  • Young Adult

Grants and funding

The authors have no support or funding to report.