A glucuronoyl esterase from Acremonium alcalophilum cleaves native lignin-carbohydrate ester bonds

FEBS Lett. 2016 Aug;590(16):2611-8. doi: 10.1002/1873-3468.12290. Epub 2016 Jul 26.

Abstract

The Glucuronoyl esterases (GE) have been proposed to target lignin-carbohydrate (LC) ester bonds between lignin moieties and glucuronic acid side groups of xylan, but to date, no direct observations of enzymatic cleavage on native LC ester bonds have been demonstrated. In the present investigation, LCC fractions from spruce and birch were treated with a recombinantly produced GE originating from Acremonium alcalophilum (AaGE1). A combination of size exclusion chromatography and (31) P NMR analyses of phosphitylated LCC samples, before and after AaGE1 treatment provided the first evidence for cleavage of the LC ester linkages existing in wood.

Keywords: 31P NMR; carbohydrate esterase; lignin-carbohydrate complexes; size exclusion chromatography; spruce and birch.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acremonium / enzymology
  • Betula / chemistry
  • Carbohydrates / chemistry*
  • Carbohydrates / immunology
  • Esterases / chemistry*
  • Esterases / metabolism
  • Esters / chemistry*
  • Esters / metabolism
  • Glucuronic Acid / chemistry
  • Lignin / chemistry
  • Picea / chemistry
  • Xylans / chemistry

Substances

  • Carbohydrates
  • Esters
  • Xylans
  • Glucuronic Acid
  • Lignin
  • Esterases