Infectious complication or exacerbation of granulomatosis with polyangiitis?

Reumatologia. 2015;53(5):286-91. doi: 10.5114/reum.2015.55833. Epub 2015 Dec 8.

Abstract

Granulomatosis with polyangiitis (GPA) is a primary, systemic small vessel vasculitis. The respiratory tract is typically involved in the course of the disease. Abnormalities on the chest radiograph are noted in more than 70% patients at some point during their disease history. In some clinical situations it is difficult to distinguish whether symptoms result from the underlying disease or are a symptom of infection. In these clinical situations, chest computed tomography (CT) can be very useful. We present a patient with GPA localized mainly in the respiratory tract with sudden deterioration of the general state and new abnormalities revealed in the CT of the chest.

Keywords: computed tomography; granulomatosis with polyangiitis; infectious complications; respiratory tract stenosis.