Neurologic and Head and Neck Manifestations of Sickle Cell Disease

Andrew Steven; Prashant Raghavan; Tanya J Rath; Dheeraj Gandhi

doi:10.1016/j.hoc.2016.03.004

Neurologic and Head and Neck Manifestations of Sickle Cell Disease

Hematol Oncol Clin North Am. 2016 Aug;30(4):779-98. doi: 10.1016/j.hoc.2016.03.004. Epub 2016 Jun 7.

Authors

Andrew Steven¹, Prashant Raghavan², Tanya J Rath³, Dheeraj Gandhi²

Affiliations

¹ Department of Diagnostic Radiology, University of Maryland Medical System, 22 S Greene St., Baltimore, MD 21201, USA. Electronic address: asteven@umm.edu.
² Department of Diagnostic Radiology, University of Maryland Medical System, 22 S Greene St., Baltimore, MD 21201, USA.
³ Department of Radiology, University of Pittsburgh Medical Center, 200 Lothrop Street, Suite 200 East Wing, Pittsburgh, PA 15213, USA.

PMID: 27443997
DOI: 10.1016/j.hoc.2016.03.004

Abstract

Sickle cell disease is a common, inherited disordered characterized by chronic hemolytic anemia with repetitive episodes of vasoocclusion resulting from deformed red blood cells. This article reviews the most significant neurologic and head and neck manifestations of this disease.

Keywords: Moyamoya; Sickle cell; Sickle cell anemia; Sickle cell disease; Stroke.

Publication types

Review

MeSH terms

Anemia, Sickle Cell* / complications
Anemia, Sickle Cell* / therapy
Head*
Humans
Neck*
Nervous System Diseases* / etiology
Nervous System Diseases* / therapy