Proband Mental Health Difficulties and Parental Stress Predict Mental Health in Toddlers at High-Risk for Autism Spectrum Disorders

J Autism Dev Disord. 2016 Oct;46(10):3242-57. doi: 10.1007/s10803-016-2861-y.

Abstract

Family-related predictors of mental health problems were investigated among 30 toddlers at familial high-risk for autism spectrum disorders (ASD) and 28 controls followed from age 2- to 3-years. Parents completed the self-report Depression Anxiety Stress Scales and the parent-report Behavior Assessment System for Children. High-risk toddlers were assessed for ASD at 3-years. Parent stress and proband mental health difficulties predicted concurrent toddler mental health difficulties at 2-years, but only baseline proband internalising problems continued to predict toddler internalising problems at 3-years; high-risk status did not confer additional risk. Baseline toddler mental health difficulties robustly predicted later difficulties, while high-risk status and diagnostic outcome conferred no additional risk. A family systems perspective may be useful for understanding toddler mental health difficulties.

Keywords: Autism spectrum disorders; Family environment; High-risk siblings; Mental health; Parent stress.

MeSH terms

  • Autism Spectrum Disorder / diagnosis
  • Autism Spectrum Disorder / psychology*
  • Child
  • Child, Preschool
  • Cohort Studies
  • Family / psychology
  • Female
  • Humans
  • Male
  • Mental Health* / trends
  • Neurodevelopmental Disorders / diagnosis
  • Neurodevelopmental Disorders / psychology*
  • Parents / psychology*
  • Predictive Value of Tests
  • Risk Factors
  • Self Report
  • Stress, Psychological / diagnosis
  • Stress, Psychological / psychology*