What Happens When Underperforming Big Ideas in Research Become Entrenched?

JAMA. 2016 Oct 4;316(13):1355-1356. doi: 10.1001/jama.2016.11076.

Authors

Michael J Joyner¹, Nigel Paneth², John P A Ioannidis³

Affiliations

¹ Laboratory of Human Integrative Physiology and Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
² Departments of Epidemiology and Biostatistics and Pediatrics and Human Development, College of Human Medicine, Michigan State University, East Lansing.
³ Stanford Prevention Research Center, Department of Medicine and Meta-Research Innovation Center at Stanford, Stanford University, Stanford, California.

PMID: 27467098
DOI: 10.1001/jama.2016.11076

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biomedical Research / economics
Biomedical Research / standards*
Disease / genetics
Electronic Health Records* / economics
Genetic Therapy* / statistics & numerical data
Genetic Variation
Humans
Molecular Targeted Therapy
National Institutes of Health (U.S.)
Neoplasms / genetics
Neoplasms / therapy
Precision Medicine* / standards
Precision Medicine* / trends
PubMed / statistics & numerical data
Publishing / statistics & numerical data
Publishing / trends
Research Support as Topic
Stem Cell Transplantation
United States