Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms

Front Surg. 2016 Jul 28:3:45. doi: 10.3389/fsurg.2016.00045. eCollection 2016.

Abstract

The current treatment of pituitary adenomas requires a balance of conservative management, surgical resection, and in select tumor types, molecular therapy. Acromegaly treatment is an evolving field where our understanding of molecular targets and drug therapies has improved treatment options for patients with excess growth hormone levels. We highlight the use of molecular therapies in this disease process and advances in this field, which may represent a paradigm shift for the future of pituitary adenoma treatment.

Keywords: Cushing disease; acromegaly; endonasal; pituitary adenoma; transsphenoidal.

Publication types

  • Review