Group A rotavirus in Brazilian bats: description of novel T15 and H15 genotypes

Arch Virol. 2016 Nov;161(11):3225-30. doi: 10.1007/s00705-016-3010-9. Epub 2016 Aug 12.

Abstract

This study aimed to survey for group A rotaviruses (RVA) in bats from Brazil and to perform phylogenetic inferences for VP4, VP7, NSP3, NSP4 and NSP5 genes. RVA was found in 9.18 % (28/305) of tested samples. The partial genotype constellation of a Molossus molossus RVA strain was G3-P[3]-Ix-Rx-Cx-Mx-Ax-Nx-T3-E3-H6, and that of a Glossophaga soricina RVA strain was G20-P[x]-Ix-Rx-Cx-Mx-Ax-Nx-T15-Ex-H15. These findings demonstrate an important role of bats in RVA epidemiology and provide evidence of participation of bat RVA strains in interspecies transmission and reassortment events.

Keywords: Bats; Genotype constellation; Rotavirus.

MeSH terms

  • Animals
  • Brazil
  • Chiroptera / virology*
  • Cluster Analysis
  • Female
  • Genotype*
  • Male
  • Molecular Epidemiology
  • Phylogeny
  • RNA, Viral / genetics
  • Rotavirus / classification*
  • Rotavirus / genetics
  • Rotavirus / isolation & purification*
  • Rotavirus Infections / veterinary*
  • Rotavirus Infections / virology
  • Sequence Analysis, DNA
  • Sequence Homology
  • Viral Proteins / genetics

Substances

  • RNA, Viral
  • Viral Proteins