Diabetic ketoacidosis in vanishing white matter

Clin Case Rep. 2016 Jun 17;4(8):717-20. doi: 10.1002/ccr3.597. eCollection 2016 Aug.

¹ Department of Pathology and Laboratory Medicine King Abdulaziz Medical City Riyadh Saudi Arabia.
² Genetics Division Department of Pediatrics King Abdulaziz Medical City Riyadh Saudi Arabia; King Saud bin Abdulaziz University for Health Science King Abdulaziz Medical City Riyadh Saudi Arabia.
³ Department of Pediatrics Prince Sultan Military Medical City Riyadh Saudi Arabia.
⁴ Department of Pathology and Laboratory Medicine King Abdulaziz Medical City Riyadh Saudi Arabia; King Saud bin Abdulaziz University for Health Science King Abdulaziz Medical City Riyadh Saudi Arabia.
⁵ Department of Pathology and Laboratory Medicine King Abdulaziz Medical City Riyadh Saudi Arabia; Department of Pediatrics College of Medicine Qassim University Almulyda Saudi Arabia.

Abstract

Clinicians should consider the EIF2B1 gene defect in any patient with diffuse white matter disease on an MRI of the brain and DKA.

Keywords: EIF2B1; diabetic ketoacidosis; hyperglycemia; vanishing white matter.