Local Recurrence of Extremity Soft Tissue Sarcoma

Whitney M Guerrero; Jeremiah L Deneve

doi:10.1016/j.suc.2016.05.002

Local Recurrence of Extremity Soft Tissue Sarcoma

Surg Clin North Am. 2016 Oct;96(5):1157-74. doi: 10.1016/j.suc.2016.05.002.

Authors

Whitney M Guerrero¹, Jeremiah L Deneve²

Affiliations

¹ Department of Surgery, University of Tennessee Health Science Center, 910 Madison Ave, Suite 300, Memphis, TN 38163, USA.
² Department of Surgery, University of Tennessee Health Science Center, 910 Madison Ave, Suite 300, Memphis, TN 38163, USA; Division of Surgical Oncology, University of Tennessee Health Science Center, 910 Madison Avenue, Suite 300, Memphis, TN 38163, USA. Electronic address: jdeneve@uthsc.edu.

PMID: 27542648
DOI: 10.1016/j.suc.2016.05.002

Abstract

The management of recurrent soft tissue sarcoma is a challenging problem for clinicians and has a significant physical, mental, emotional, and oncologic impact for the patient. Despite excellent limb-preservation therapies, approximately one-quarter of patients may eventually develop recurrence of disease. How to most appropriately manage these patients is a matter of debate. Several treatment options exist, including surgical resection, irradiation, systemic chemotherapy, amputation, and regional therapies. This article highlights the management of recurrent extremity soft tissue sarcoma.

Keywords: Amputation; Hyperthermic isolated limb perfusion; Isolated limb infusion; Limb salvage; Metastasis; Radiation; Recurrence; Sarcoma.

Publication types

Review

MeSH terms

Combined Modality Therapy
Disease Management*
Extremities
Humans
Neoplasm Recurrence, Local / prevention & control*
Sarcoma / therapy*