Treatment of Metastatic Prostate Cancer in Older Adults

Curr Oncol Rep. 2016 Oct;18(10):63. doi: 10.1007/s11912-016-0548-3.

Abstract

The aging of the population, along with rising life expectancy, means that increasing numbers of older men will be diagnosed with prostate cancer, and a large proportion of these men will present with metastatic disease. In this paper, we discuss recent advances in prostate cancer treatment. In particular, we review management approaches for older patients with metastatic prostate cancer based on the decision tree developed by the International Society of Geriatric Oncology, which categorized older men as "fit," "vulnerable," and "frail" according to comprehensive geriatric assessment.

Keywords: Geriatric assessment; Older adults; Prostate cancer.

Publication types

  • Review

MeSH terms

  • Aged
  • Aging
  • Antineoplastic Agents / therapeutic use*
  • Clinical Trials as Topic
  • Geriatric Assessment
  • Humans
  • Male
  • Neoplasm Metastasis / pathology
  • Neoplasm Metastasis / therapy*
  • Orchiectomy / methods*
  • Prostatic Neoplasms / pathology*
  • Prostatic Neoplasms / therapy*

Substances

  • Antineoplastic Agents