Frequency of anti- Toxoplasma gondii IgA, IgM, and IgG antibodies in high-risk pregnancies, in Brazil

Rev Soc Bras Med Trop. 2016 Jul-Aug;49(4):512-4. doi: 10.1590/0037-8682-0046-2016.

Abstract

Introduction: Toxoplasmosis during pregnancy can be severe; thus, it is essential to diagnose the disease via serological tests.

Methods: An enzyme-linked immunosorbent assay (ELISA) was used to investigate anti-Toxoplasma gondii immunoglobulin A (IgA), M (IgM) and G (IgG) antibodies in 62 high-risk pregnant women.

Results: Forty-three (69.4%) women were positive for IgA, 31 (50%) for IgG, and 57 (91.9%) for IgM; 4 (6,5%) were positive for IgA but negative for IgM; 10 (16.1%) were negative for IgA and IgM but positive for IgG.

Conclusions: Testing for these antibodies can help diagnose infection in pregnant women, thereby contributing to clinical management.

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Protozoan / blood*
  • Brazil
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Immunoglobulin A / blood*
  • Immunoglobulin G / blood*
  • Immunoglobulin M / blood*
  • Pregnancy
  • Pregnancy Complications, Parasitic / diagnosis*
  • Pregnancy Complications, Parasitic / immunology
  • Pregnancy, High-Risk / immunology
  • Toxoplasma / immunology*
  • Young Adult

Substances

  • Antibodies, Protozoan
  • Immunoglobulin A
  • Immunoglobulin G
  • Immunoglobulin M