Reversal of congenital hypogonadotropic hypogonadism in a man with Kallmann syndrome due to SOX10 mutation

Clin Endocrinol (Oxf). 2016 Dec;85(6):988-989. doi: 10.1111/cen.13231. Epub 2016 Oct 3.

Authors

Luigi Maione^{1

2

3}, Sylvie Brailly-Tabard^{2

3

4}, Jérôme Nevoux^{4

5}, Jérôme Bouligand^{2

3

4}, Jacques Young^{1

3

4}

Affiliations

¹ Department of Reproductive Endocrinology, Assistance Publique-Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin Bicêtre, France.
² Department of Molecular Genetics and Hormonology, Assistance Publique-Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin Bicêtre, France.
³ University of Paris-Sud, Le Kremlin Bicêtre, France.
⁴ INSERM UMR-1185, Le Kremlin Bicêtre, France.
⁵ Otorhinolaryngology Department, Bicêtre Hospital, Le Kremlin Bicêtre, France.

PMID: 27616149
DOI: 10.1111/cen.13231

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
Androgens / therapeutic use
Humans
Hypogonadism / blood
Hypogonadism / congenital*
Hypogonadism / drug therapy
Kallmann Syndrome / blood
Kallmann Syndrome / diagnosis
Kallmann Syndrome / genetics*
Luteinizing Hormone / blood
Male
Mutation*
Organ Size
Remission Induction
SOXE Transcription Factors / genetics*
Testis / pathology
Testosterone / therapeutic use
Young Adult

Substances

Androgens
SOX10 protein, human
SOXE Transcription Factors
Testosterone
Luteinizing Hormone