Feasibility of a short term severely restricted sodium diet with counselling support

Ann Clin Biochem. 1989 Jul:26 ( Pt 4):358-60. doi: 10.1177/000456328902600411.

Abstract

For the purpose of short term clinical trials previous studies have made use of metabolic kitchens to provide severely restricted sodium diets. We evaluated the feasibility of administering a 5-day severely restricted (22 mmol) sodium diet on an outpatient basis with counselling support, outside a metabolic unit. In 13 highly-motivated volunteers, 24-h urinary sodium excretion fell from 128.5 +/- 11.9 on a normal diet to 19.2 +/- 2.88 mmol per day and plasma sodium dropped from normal diet to 19.2 +/- 2.88 mmol per day and plasma sodium dropped from 140 +/- 0.41 to 137 +/- 0.78 mmol/L, showing that such an approach is effective.

MeSH terms

  • Adult
  • Counseling*
  • Diet, Sodium-Restricted*
  • Feasibility Studies
  • Female
  • Glomerular Filtration Rate
  • Hematocrit
  • Humans
  • Male
  • Middle Aged
  • Patient Compliance
  • Sodium / urine

Substances

  • Sodium