1 Department of Intensive Care, Erasme University Hospital, Unversité Libre de Bruxelles, Brussels, Belgium. jlvincent@intensive.org.
2 Multidisciplinary Intensive Care, Department of Clinical Medicine, Trinity College, Welcome Trust-HRB Clinical Research Facility, St James's University Hospital, Dublin, Ireland.
3 CIBER de Enfermedades Respiratorias (CIBERes), Madrid, Spain.
4 General Intensive Care Unit, Raymond Poincaré Hospital (APHP), Laboratory of Infection and Inflammation, U1173 INSERM and University of Versailles, 92380, Garches, France.