An unusual case of Candida ciferrii fungemia in an immunocompromised patient with Crohn's and Mycobacterium bovis disease

J Infect Dev Ctries. 2016 Oct 31;10(10):1156-1158. doi: 10.3855/jidc.8228.

Abstract

We present a case report of a fungal bloodstream infection due to an unusual pathogen. This is a 30 years-old female patient diagnosed with Crohn's disease and a disseminated Mycobacterium bovis infection subsequently complicated by fungemia due to the emergent yeast pathogen Candida ciferrii, who was unresponsive to fluconazole and made a full recovery after treatment with posaconazole. To our knowledge, this is the first report of Candida ciferrii isolation from blood in an adult associated to a central venous catheter and which was successfully treated with posaconazole.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antifungal Agents / administration & dosage
  • Candida / classification
  • Candida / isolation & purification*
  • Candidemia / diagnosis*
  • Candidemia / drug therapy
  • Candidemia / pathology
  • Catheter-Related Infections / diagnosis*
  • Catheter-Related Infections / drug therapy
  • Catheter-Related Infections / pathology
  • Catheterization, Central Venous / adverse effects
  • Crohn Disease / complications*
  • Female
  • Humans
  • Immunocompromised Host
  • Mycobacterium bovis / isolation & purification*
  • Treatment Outcome
  • Triazoles / administration & dosage
  • Tuberculosis / complications*

Substances

  • Antifungal Agents
  • Triazoles
  • posaconazole