A novel sensitive colorimetric sensor for Cu2+ based on in situ formation of fluorescent quantum dots with photocatalytic activity

Abstract

This work demonstrates the use of quantum dots (QDs) with photocatalytic activity as a sensitive, inexpensive and rapid colorimetric platform for Cu²⁺ sensing. Based on the simple thiol compound mediated QDs growing method, CdS QDs can be quickly formed in situ, which possess excellent photocatalytic ability for the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) to produce a colored product under light irradiation. Cu²⁺ can catalyze the oxidation of sulfhydryl groups in glutathione (GSH) which act as a stabilizer for CdS QDs. In the presence of Cu²⁺, GSH is oxidized and loss the stabilization ability for the growth of CdS QDs, thus resulting in the decrease of the absorbance. Under optimum conditions, as low as 5.3nM Cu²⁺ can be detected. This sensing system is simple, reliable and holds great potential to provide a new general platform for ultrasensitive monitoring of a variety of analytes.

Keywords: Colorimetric sensor; Copper ions; Photocatalytic activity; Quantum dots.