Serum β-hCG as an Indicator of Recurrence After the Complete Resection of a Malignant Solitary Fibrous Tumor of the Pleura

Ann Thorac Surg. 2016 Dec;102(6):e551-e553. doi: 10.1016/j.athoracsur.2016.05.061.

Abstract

In solitary fibrous tumors (SFTs) of the pleura, malignant SFTs are uncommon. Although SFTs are known to cause paraneoplastic syndromes through the production of insulin-like growth factor, to the best of our knowledge, the production of beta-human chorionic gonadotropin (β-hCG) has been reported only in 1 case involving a patient with a benign SFT. We herein report the first case of the elevation of β-hCG serum levels associated with a malignant SFT in which the β-hCG serum level became a useful indicator of recurrence after the complete resection of the primary mediastinal lesion.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Chorionic Gonadotropin, beta Subunit, Human / blood*
  • Humans
  • Male
  • Neoplasm Recurrence, Local / blood*
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Recurrence, Local / etiology
  • Solitary Fibrous Tumor, Pleural / blood*
  • Solitary Fibrous Tumor, Pleural / pathology
  • Solitary Fibrous Tumor, Pleural / surgery*

Substances

  • Chorionic Gonadotropin, beta Subunit, Human