Effect of mechanical vibration on transcutaneous oxygen levels in the feet of type 2 diabetes mellitus patients

Abstract

Background and objective: Foot conditions in patients with diabetes mellitus (DM) are major causes of morbidity and disability. Whole body vibration may promote blood circulation in the lower limbs, hence facilitating perfusion and promoting the supply of nutrients and oxygen to comprised tissues. Transcutaneous oxygen levels (TcPO₂)>40mmHg in cases of diabetic foot syndrome are associated with a good prognosis in the resolution of ulcers. The objective of this study was to determine whether whole body vibration favors some parameters of interest related to complications associated with the diabetic foot syndrome.

Patients and methods: Fifty-four patients with DM were included in a 12-week exercise program based on whole body vibration. Glycemic control was determined on the basis of the patients' levels of glycated hemoglobin (HbA_1c); sensitivity and TcPO₂ levels of each foot were also recorded. Assessments were performed prior to initiating the whole body vibration program and at the end of it.

Results: No significant changes were observed in the patients' HbA_1c (P=.442) levels or sensitivity (P=.07). A significant 7mmHg increase (P<.0001; effect size: d=0.53) was observed in the concentration of TcPO₂.

Conclusions: Whole body vibration may increase TcPO₂ levels with useful implications for the prevention or management of complications associated with restricted blood perfusion in the diabetic foot syndrome.

Keywords: Diabetes mellitus; Diabetic foot; Oximetría transcutánea; Pie diabético; Transcutaneous oximetry; Vibración de cuerpo completo; Whole body vibration.