A new acute myeloid leukemia case with STAT5B-RARA gene fusion due to 17q21.2 interstitial deletion

Leuk Lymphoma. 2017 Aug;58(8):1977-1980. doi: 10.1080/10428194.2016.1262952. Epub 2016 Dec 2.

Authors

Affiliations

¹ a SMeL Citogenetica e Genetica Medica, ASST Sette Laghi , Varese , Italy.
² b Dipartimento di Medicina Specialistica, Ematologia , ASST Sette Laghi , Varese , Italy.
³ c Dipartimento di Scienze Chirurgiche e Morfologiche , Università degli Studi dell'Insubria , Varese , Italy.
⁴ d Dipartimento di Medicina Clinica e Sperimentale, Ematologia , Università degli Studi dell'Insubria , Varese , Italy.

PMID: 27911132
DOI: 10.1080/10428194.2016.1262952

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / adverse effects
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biopsy
Blood Cell Count
Bone Marrow / pathology
Chromosome Deletion*
Chromosomes, Human, Pair 17*
Comparative Genomic Hybridization
Humans
Immunophenotyping
In Situ Hybridization, Fluorescence
Leukemia, Myeloid, Acute / diagnosis*
Leukemia, Myeloid, Acute / drug therapy
Leukemia, Myeloid, Acute / genetics*
Male
Oncogene Proteins, Fusion / genetics*
STAT5 Transcription Factor / genetics*
Treatment Outcome

Substances

Oncogene Proteins, Fusion
STAT5 Transcription Factor
STAT5-RARalpha protein, human