The Retinopathy of Prematurity (ROP) epidemic is no more confined to metro cities and has spread to interior states including Eastern India. There is hardly any published data available on the subject, including the incidence and profile of babies with ROP, screening experience with binocular indirect ophthalmoscope and wide-field digital retinal imaging, as well as the difficulties faced with each model. In our cohort, 33.2% had ROP and 25.3% of babies with ROP required treatment. Mean (SD) gestational age and birth weight were 30.7 (2.53) weeks (range: 23 to 37 weeks) and 1315.09 (322.30) grams (range: 650-2500 grams), respectively. The hurdles in establishing a screening program are discussed. Binocular indirect opththalmoscopy and wide-field digital retinal imaging were complementary rather than a substitute for each other in a non-telescreening model.