Late Allograft Renal Vein Thrombosis Treated With Anticoagulation Alone: A Case Report

Transplant Proc. 2016 Nov;48(9):3095-3098. doi: 10.1016/j.transproceed.2016.09.006.

Abstract

Background: Allograft renal vein thrombosis is a rare complication of kidney transplantation. Most cases occur in the first 2 weeks after transplantation, but there are cases described many years after the transplant surgery. Allograft loss is the usual outcome.

Methods: We present a case of a renal transplant recipient with allograft renal vein thrombosis associated with deep venous thrombosis of a lower limb, 9 years after transplantation. He was successfully treated with anticoagulation alone, with recovery of allograft function.

Results: The patient was given unfractioned heparin and elastic compression stockings. Five days later, the patient recovered diuresis and hemodialysis treatment was discontinued. Doppler ultrasound was done and revealed partial re-permeabilization of allograft renal vein, with maximal velocity of 15 cm/s. After 30 months of follow-up, the patient was maintained on oral anticoagulation with warfarin, and no thromboembolic or hemorrhagic events were documented. The patient's serum creatinine was stable, between 1.6 and 1.8 mg/dL.

Conclusions: Our patient demonstrated that anticoagulation alone and dialytic support might be able to promote total recovery of allograft function after renal vein thrombosis.

Publication types

  • Case Reports

MeSH terms

  • Allografts
  • Anticoagulants / therapeutic use*
  • Heparin / therapeutic use
  • Humans
  • Kidney Transplantation / adverse effects*
  • Male
  • Middle Aged
  • Postoperative Complications / drug therapy
  • Postoperative Complications / etiology
  • Renal Dialysis
  • Renal Veins
  • Stockings, Compression
  • Transplantation, Homologous
  • Venous Thrombosis / drug therapy*
  • Venous Thrombosis / etiology
  • Warfarin / therapeutic use

Substances

  • Anticoagulants
  • Warfarin
  • Heparin