Data on polymorphism of XRCC1 and cervical cancer risk from South India

Geethakumari Konathala; Ramesh Mandarapu; Sudhakar Godi

doi:10.1016/j.dib.2016.11.052

Data on polymorphism of XRCC1 and cervical cancer risk from South India

Data Brief. 2016 Nov 26:10:11-13. doi: 10.1016/j.dib.2016.11.052. eCollection 2017 Feb.

Authors

Geethakumari Konathala¹, Ramesh Mandarapu¹, Sudhakar Godi¹

Affiliation

¹ Department of Human Genetics, Andhra University, Visakhapatnam 530003, Andhra Pradesh, India.

Abstract

X-ray repair cross-complementing group 1 (XRCC1) is a major DNA repair gene involved in BER mutation. Polymorphisms in DNA repair genes associated with repair efficiency against DNA damage may predispose an individual׳s cancer susceptibility. Data from cervical cancer patients was collected from South Indian Women. Genotyping of XRCC1 polymorphisms (194C/T, 280G/A and 399G/A) was done by polymerase-chain-reaction with the confronting-two-pair primer (PCR-CTPP) method.

Keywords: DNA Repair Genes; Indian population; Polymorphism; XRCC1.