Polypoidal Choroidal Vasculopathy Occurring in the Context of Large Colloid Drusen

Ophthalmic Surg Lasers Imaging Retina. 2016 Dec 1;47(12):1154-1156. doi: 10.3928/23258160-20161130-12.

Abstract

The authors report, for the first time, an association between large colloid drusen (LCD) and choroidal neovascularization in a 58-year-old man. Multimodal imaging confirmed the diagnosis of LCD in both eyes and polypoidal choroidal vasculopathy in the left eye. The patient was treated with monthly intravitreal injections of aflibercept (Eylea; Regeneron, Tarrytown, NY). The authors hypothesize that these deposits are probably associated with retinal pigment epithelium dysfunction and could thus lead to delayed neovascularization and atrophy. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:1154-1156.].

Publication types

  • Case Reports

MeSH terms

  • Choroid / blood supply
  • Choroid / pathology*
  • Choroidal Neovascularization / diagnosis*
  • Choroidal Neovascularization / drug therapy
  • Choroidal Neovascularization / etiology
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Intravitreal Injections
  • Male
  • Middle Aged
  • Polyps / diagnosis*
  • Polyps / drug therapy
  • Receptors, Vascular Endothelial Growth Factor / administration & dosage
  • Receptors, Vascular Endothelial Growth Factor / antagonists & inhibitors
  • Recombinant Fusion Proteins / administration & dosage
  • Retinal Drusen / complications*
  • Retinal Drusen / diagnosis
  • Retinal Drusen / drug therapy
  • Retinal Pigment Epithelium / pathology*
  • Tomography, Optical Coherence / methods
  • Visual Acuity

Substances

  • Recombinant Fusion Proteins
  • aflibercept
  • Receptors, Vascular Endothelial Growth Factor