Abdominal organ procurement in the Netherlands - an analysis of quality and clinical impact

Transpl Int. 2017 Mar;30(3):288-294. doi: 10.1111/tri.12906. Epub 2017 Feb 8.

Abstract

Between March 2012 and August 2013, 591 quality forms were filled out for abdominal organs in the Netherlands. In 133 cases (23%), there was a discrepancy between the evaluation from the procuring and transplanting surgeons. Injuries were seen in 148 (25%) organs of which 12 (2%) led to discarding of the organ: one of 133 (0.8%) livers, five of 38 (13%) pancreata and six of 420 (1.4%) kidneys (P < 0.001). Higher donor BMI was a risk factor for procurement-related injury in all organs (OR: 1.06, P = 0.011) and donor after cardiac death (DCD) donation in liver procurement (OR: 2.31, P = 0.034). DCD donation is also associated with more pancreata being discarded due to injury (OR: 10.333, P = 0.046). A higher procurement volume in a centre was associated with less injury in pancreata (OR = -0.95, P = 0.013) and kidneys (OR = -0.91, P = 0.012). The quality form system efficiently monitors the quality of organ procurement. Although there is a relatively high rate of organ injury, the discard rate is low and it does not significantly affect 1-year graft survival for any organ. We identified higher BMI as a risk factor for injury in abdominal organs and DCD as a risk factor in livers. A higher procurement volume is associated with fewer injuries.

Keywords: complications; organ donation; organ procurement; quality.

MeSH terms

  • Donor Selection / methods
  • Donor Selection / standards
  • Female
  • Graft Survival
  • Humans
  • Kidney Transplantation
  • Liver Transplantation
  • Male
  • Netherlands
  • Pancreas Transplantation
  • Prospective Studies
  • Risk Factors
  • Tissue and Organ Harvesting / methods*
  • Tissue and Organ Harvesting / standards
  • Tissue and Organ Procurement / methods*
  • Tissue and Organ Procurement / standards