Impact of FLT3-ITD diversity on response to induction chemotherapy in patients with acute myeloid leukemia

Haematologica. 2017 Apr;102(4):e129-e131. doi: 10.3324/haematol.2016.157180. Epub 2016 Dec 29.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Motifs
  • Base Sequence
  • Cytarabine / therapeutic use
  • Gene Expression
  • Genetic Variation*
  • Humans
  • Idarubicin / therapeutic use
  • Induction Chemotherapy / methods*
  • Leukemia, Myeloid, Acute / drug therapy
  • Leukemia, Myeloid, Acute / genetics*
  • Leukemia, Myeloid, Acute / mortality
  • Leukemia, Myeloid, Acute / pathology
  • Mitoxantrone / therapeutic use
  • Protein Domains
  • Retrospective Studies
  • Sequence Analysis, DNA
  • Survival Analysis
  • Tandem Repeat Sequences*
  • fms-Like Tyrosine Kinase 3 / chemistry
  • fms-Like Tyrosine Kinase 3 / genetics*
  • fms-Like Tyrosine Kinase 3 / metabolism

Substances

  • Cytarabine
  • Mitoxantrone
  • FLT3 protein, human
  • fms-Like Tyrosine Kinase 3
  • Idarubicin