Glucose homeostasis abnormalities among Cameroon patients with newly diagnosed hypertension

J Clin Hypertens (Greenwich). 2017 May;19(5):519-523. doi: 10.1111/jch.12959. Epub 2017 Jan 2.

Abstract

The authors assessed the frequency of glucose homeostasis abnormalities among 839 Cameroonians with newly diagnosed hypertension (mean age: 50.8±11 years; 49.9% female) in a cross-sectional survey conducted at the Douala General Hospital, Douala, Cameroon. In all participants, blood pressure, fasting plasma glucose (FPG), and lipids were recorded. Impaired fasting glycemia was described as an FPG level between 100 and 125 mg/dL and provisional diabetes as an FPG level ≥126 mg/dL. The FPG was 101±30 mg/dL. The overall proportion of abnormal glucose homeostasis was 38.3%, while 7.7% of patients (n=65) had known diabetes. A total of 23.7% (n=199) had impaired fasting glycemia and 6.8% (n=57) had provisional diabetes. Multivariable logistic regression revealed that male sex (odds ratio [OR], 1.53; 95% confidence interval [CI], 1.15-2.06), age older than 55 years (OR, 1.55; 95% CI, 1.15-2.09), and low-density lipoprotein cholesterol >1 g/L (OR, 1.34; 95% CI, 1.00-1.82) were independently associated with abnormal glucose homeostasis (all P<.05). Glucose homeostasis abnormalities are highly prevalent among Cameroonian patients with newly diagnosed hypertension.

Keywords: Cameroon; cardiovascular risk factors; diabetes; glucose homeostasis abnormalities; hypertension; impaired fasting glycemia; provisional diabetes.

MeSH terms

  • Blood Glucose / analysis*
  • Blood Pressure / physiology
  • Blood Pressure Determination / methods
  • Cameroon / epidemiology
  • Cholesterol, LDL
  • Cross-Sectional Studies
  • Diabetes Mellitus / blood
  • Diabetes Mellitus / epidemiology
  • Fasting / blood*
  • Female
  • Homeostasis
  • Humans
  • Hypertension / blood*
  • Hypertension / diagnosis*
  • Hypertension / epidemiology
  • Lipids / blood
  • Male
  • Middle Aged
  • Prediabetic State / blood
  • Prediabetic State / epidemiology
  • Prevalence
  • Risk Factors

Substances

  • Blood Glucose
  • Cholesterol, LDL
  • Lipids