Acute sarcoid myopathy: a case report and literature review

Sarcoidosis Vasc Diffuse Lung Dis. 2016 Dec 23;33(4):413-415.

Abstract

Sarcoidosis is a worldwide spread disease with brad clinical spectrum, in which the pulmonary involvement is the main manifestation (more than 90% of cases); nevertheless, extrathoracic symptoms can predominate in the clinical picture and they may even be the first manifestation. One of them is the skeletal muscle involvement that normally is chronic and silent, with poor response to treatment with glucocorticoids. However, in some cases, it has an acute presentation. We present a case of a 61-year-old man with diagnosis of sarcoidosis whe were evaluated for proximal lower limb weakness within few days of evolution.

Keywords: Granulomatous disease; Myopathy; Sarcoidosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Biopsy
  • Drug Therapy, Combination
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunohistochemistry
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Middle Aged
  • Muscle Strength
  • Muscle Weakness / diagnosis*
  • Muscle Weakness / pathology
  • Muscle Weakness / physiopathology
  • Muscle, Skeletal* / drug effects
  • Muscle, Skeletal* / pathology
  • Muscle, Skeletal* / physiopathology
  • Recovery of Function
  • Sarcoidosis / diagnosis*
  • Sarcoidosis / drug therapy
  • Sarcoidosis / pathology
  • Sarcoidosis / physiopathology
  • Treatment Outcome

Substances

  • Glucocorticoids
  • Immunosuppressive Agents