Prevalence of metabolic syndrome in pre- and postmenopausal women

Arch Endocrinol Metab. 2017 Mar-Apr;61(2):160-166. doi: 10.1590/2359-3997000000253. Epub 2017 Feb 16.

Abstract

Objective: The objective of this study was to determine the prevalence of metabolic syndrome (MS) and its components among pre- and postmenopausal women, as well as the association between menopausal status and MS.

Materials and methods: A retrospective study was conducted at a reference cardiology outpatient clinic in a city located in Northwestern Paraná State, Brazil. A total of 958 medical records of symptomatic climacteric women evaluated between 2010 and 2014 were analyzed. The study consisted of two groups: pre- and post-menopausal women. MS was characterized according to the criteria of the National Cholesterol Education Program's Adult Treatment Panel III - NCEP-ATP III-2005.

Results: MS was observed in 18.5% of the total study population; 9.4% of the premenopausal women and 22.2% of the postmenopausal women displayed MS, corresponding to a relative risk of 2.75. In addition, the frequency of MS increased with age. Regarding the components of MS, postmenopausal women were more likely to have high density lipoprotein (HDL-C) levels < 50 mg/dL; systolic blood pressure (SBP) values ≥ 130 mmHg or diastolic blood pressure (DBP) values ≥ 85 mmHg; and fasting glucose levels ≥ 100 mg/dL.

Conclusion: MS was more prevalent among postmenopausal women than among premenopausal women.

MeSH terms

  • Adult
  • Age Distribution
  • Age Factors
  • Aged
  • Blood Glucose / analysis
  • Blood Pressure / physiology
  • Brazil / epidemiology
  • Cholesterol / blood
  • Female
  • Humans
  • Hypercholesterolemia / epidemiology
  • Hypertension / epidemiology
  • Hypertriglyceridemia / epidemiology
  • Metabolic Syndrome / epidemiology*
  • Middle Aged
  • Postmenopause*
  • Premenopause*
  • Prevalence
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Triglycerides / blood

Substances

  • Blood Glucose
  • Triglycerides
  • Cholesterol