Synthesis, binding studies, and structure-activity relationships of 1-aryl-and 2-aryl[1]benzopyranopyrazol-4-ones, central benzodiazepine receptor ligands

J Med Chem. 1988 Jan;31(1):1-3. doi: 10.1021/jm00396a001.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Benzopyrans / chemical synthesis*
  • Benzopyrans / pharmacology
  • Brain / metabolism
  • Cattle
  • Cell Membrane / metabolism
  • Flunitrazepam / metabolism
  • Indicators and Reagents
  • Ligands
  • Pyrazines / chemical synthesis*
  • Pyrazines / pharmacology
  • Pyrazoles / chemical synthesis
  • Pyrazolones*
  • Receptors, GABA-A / drug effects
  • Receptors, GABA-A / metabolism*
  • Structure-Activity Relationship

Substances

  • Benzopyrans
  • Indicators and Reagents
  • Ligands
  • Pyrazines
  • Pyrazoles
  • Pyrazolones
  • Receptors, GABA-A
  • pyrazolone
  • Flunitrazepam