Acute Hematogenous Osteomyelitis in Children: Pathogenesis, Diagnosis, and Treatment

Shawn S Funk; Lawson A B Copley

doi:10.1016/j.ocl.2016.12.007

Acute Hematogenous Osteomyelitis in Children: Pathogenesis, Diagnosis, and Treatment

Orthop Clin North Am. 2017 Apr;48(2):199-208. doi: 10.1016/j.ocl.2016.12.007.

Authors

Shawn S Funk¹, Lawson A B Copley²

Affiliations

¹ Department of Orthopaedic Surgery, The Children's Hospital of San Antonio, Baylor College of Medicine, 315 North San Saba Street, Suite 1135, San Antonio, TX 78207, USA.
² Department of Orthopaedic Surgery, Children's Medical Center of Dallas, University of Texas Southwestern, 1935 Medical District Drive, Dallas, TX 75235, USA. Electronic address: lawson.copley@childrens.com.

PMID: 28336042
DOI: 10.1016/j.ocl.2016.12.007

Abstract

Acute hematogenous osteomyelitis (AHO) in children is an ideal condition to study due to its representation of a wide spectrum of disorders that comprise pediatric musculoskeletal infection. Proper care for children with AHO is multidisciplinary and collaborative. AHO continues to present a significant clinical challenge due to evolving epidemiology and complex pathogenesis. A guideline-driven, multidisciplinary approach has been introduced and shown to effectively reduce hospital stay, improve the timing and selection of empirical antibiotic administration, reduce delay to initial MRI, reduce the rate of readmission, and shorten antibiotic duration.

Keywords: Acute hematogenous osteomyelitis; Children; Diagnosis; Pathogenesis; Treatment.

Publication types

Review

MeSH terms

Bacteremia* / complications
Bacteremia* / diagnosis
Bacteremia* / prevention & control
Child
Disease Management
Humans
Osteomyelitis* / blood
Osteomyelitis* / diagnosis
Osteomyelitis* / microbiology
Osteomyelitis* / therapy