Abstract
A case of sensorimotor polyneuropathy during disulfiram administration is described. This complication partially resolved after the medication was stopped. Pathological observations revealed axonal changes and neurofilament accumulation was found in a few myelinated and unmyelinated axons.
MeSH terms
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Alcoholism / drug therapy*
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Disulfiram / adverse effects*
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Humans
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Male
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Microscopy, Electron
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Middle Aged
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Motor Neurons / drug effects
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Motor Neurons / ultrastructure
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Neurons, Afferent / drug effects
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Neurons, Afferent / ultrastructure
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Peripheral Nervous System Diseases / chemically induced*
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Peripheral Nervous System Diseases / pathology