Strategies for HCC target discovery

Aging (Albany NY). 2017 Apr;9(4):1088-1089. doi: 10.18632/aging.101233.

Authors

Pedro Molina-Sánchez^{1

2}, Amaia Lujambio^{1

2

3}

Affiliations

¹ Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
² Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
³ Graduate School of Biomedical Sciences at Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

No abstract available

Keywords: CRISPR; RNAi; hepatocellular carcinoma; loss-of-function screens; precision medicine.

Publication types

Editorial

MeSH terms

Carcinoma, Hepatocellular / drug therapy*
Carcinoma, Hepatocellular / genetics*
Clustered Regularly Interspaced Short Palindromic Repeats
Drug Discovery / methods*
Genetic Testing / methods*
Humans
Liver Neoplasms / drug therapy*
Liver Neoplasms / genetics*
Molecular Targeted Therapy
RNA, Small Interfering / genetics
Sorafenib / therapeutic use

Substances

RNA, Small Interfering
Sorafenib