First genetic characterization of newcastle disease viruses from Namibia: identification of a novel VIIk subgenotype

Arch Virol. 2017 Aug;162(8):2427-2431. doi: 10.1007/s00705-017-3389-y. Epub 2017 May 3.

Abstract

The complete sequences of the fusion (F) protein genes of six Newcastle disease virus (NDV) isolates from backyard poultry in Namibia in 2016 have been determined. The F gene cleavage site motif for all of the isolates was 112RRQKRF117, indicating that the viruses are virulent. A phylogenetic analysis using the full F gene sequence revealed that the viruses belong to a novel subgenotype, VIIk. This is the first genetic characterization of NDV isolates from Namibia, and the findings have important implications for Newcastle disease management and control in the region.

Keywords: Namibia; Newcastle disease; phylogenetic analysis; poultry; subgenotype VIIk.

MeSH terms

  • Animals
  • Base Sequence
  • Genes, Viral
  • Genotype
  • Namibia / epidemiology
  • Newcastle Disease / epidemiology
  • Newcastle Disease / virology*
  • Newcastle disease virus / classification
  • Newcastle disease virus / genetics*
  • Newcastle disease virus / isolation & purification*
  • Phylogeny
  • Poultry
  • Poultry Diseases / epidemiology
  • Poultry Diseases / virology*
  • Viral Fusion Proteins / genetics*

Substances

  • Viral Fusion Proteins