Liver transplantation for unresectable colorectal liver metastases: A systematic review

J Surg Oncol. 2017 Sep;116(3):288-297. doi: 10.1002/jso.24671. Epub 2017 May 17.

Abstract

The use of liver transplantation (LT) for liver metastases attempted in the early 1990's was associated with poor perioperative outcomes and unacceptably low overall survival. Recently, there has been renewed interest in LT as a treatment option for colorectal liver metastases (CLM) in countries where organ supply is high. To date, no meticulous analysis about the efficacy, safety and outcomes of LT in CLM patients has been published. We present the first systematic review on the subject.

Keywords: colorectal liver metastases; liver transplantation; unresectable.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Colorectal Neoplasms / pathology*
  • Hepatectomy
  • Humans
  • Liver Neoplasms / secondary*
  • Liver Neoplasms / surgery*
  • Liver Transplantation*
  • Tissue and Organ Procurement