The promising therapeutic agents for heart diseases: Histone Methyltransferase inhibitors

Ding-Sheng Jiang; Zemin Fang; Xue-Hai Zhu; Xiang Wei

doi:10.1016/j.ijcard.2017.04.010

The promising therapeutic agents for heart diseases: Histone Methyltransferase inhibitors

Int J Cardiol. 2017 Jul 15:239:6. doi: 10.1016/j.ijcard.2017.04.010.

Authors

Ding-Sheng Jiang¹, Zemin Fang², Xue-Hai Zhu³, Xiang Wei⁴

Affiliations

¹ Division of Cardiothoracic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Key Laboratory of Organ Transplantation, Ministry of Education, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Key Laboratory of Organ Transplantation, Ministry of Health, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
² Division of Cardiothoracic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
³ Division of Cardiothoracic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Key Laboratory of Organ Transplantation, Ministry of Education, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Key Laboratory of Organ Transplantation, Ministry of Health, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. Electronic address: 13072724207@163.com.
⁴ Division of Cardiothoracic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Key Laboratory of Organ Transplantation, Ministry of Education, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Key Laboratory of Organ Transplantation, Ministry of Health, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. Electronic address: xiangwei@tjh.tjmu.edu.cn.

PMID: 28560987
DOI: 10.1016/j.ijcard.2017.04.010

No abstract available

Keywords: Epigenetics; Heart disease; Histone Methyltransferase; Inhibitor.

Publication types

Letter
Comment

MeSH terms

Enzyme Inhibitors
Epigenesis, Genetic / drug effects*
Heart Diseases
Histone Deacetylase Inhibitors
Histone Methyltransferases
Histone-Lysine N-Methyltransferase*
Humans

Substances

Enzyme Inhibitors
Histone Deacetylase Inhibitors
Histone Methyltransferases
Histone-Lysine N-Methyltransferase