Emerging Treatment Models in Rheumatology: IgG4-Related Disease: Insights Into Human Immunology and Targeted Therapies

Arthritis Rheumatol. 2017 Sep;69(9):1722-1732. doi: 10.1002/art.40168. Epub 2017 Aug 8.

Authors

Cory A Perugino¹, Hamid Mattoo², Vinay S Mahajan², Takashi Maehara², Zachary S Wallace³, Shiv Pillai², John H Stone³

Affiliations

¹ Massachusetts General Hospital, Boston, and Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
² Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts.
³ Massachusetts General Hospital, Boston.

No abstract available

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Biopsy
CD4-Positive T-Lymphocytes / immunology
Disease Models, Animal
Glucocorticoids / therapeutic use
Humans
Immunity, Humoral / immunology*
Immunoglobulin G / immunology*
Immunoglobulin G4-Related Disease / drug therapy
Immunoglobulin G4-Related Disease / immunology*
Immunologic Factors / therapeutic use
Lymphocyte Depletion
Mice
Molecular Targeted Therapy
Plasma Cells / immunology*
Precursor Cells, B-Lymphoid / immunology*
Rituximab / therapeutic use
T-Lymphocyte Subsets / immunology
T-Lymphocytes, Helper-Inducer / immunology
Th2 Cells / immunology*
Translational Research, Biomedical

Substances

Glucocorticoids
Immunoglobulin G
Immunologic Factors
Rituximab

Grants and funding