This article focuses on the understanding of the biochemistry and surgical application of bone substitute materials (BSMs) and particularly the newer calcium phosphate materials that can form a structural orthobiologic matrix within the metaphyseal components of the periarticular bone. Six characteristics of BSMs are detailed that can be used as a guide for the proper selection and application of the optimal BSM type for periarticular fracture repair. These 6 characteristics of BSMs are divided into 2 pillars. One pillar details the 3 biochemical features of BSMs and the other pillar details the 3 surgical application properties.
Keywords: Bone augmentation; Bone substitute materials (BSM); Calcium phosphate cements (CPC); Calcium phosphates; Compromised bone; Internal fixation; Minimally Invasive Surgery (MIS); Structural orthobiologic matrix (SOM).
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