Left Main Percutaneous Coronary Intervention

Neil Ruparelia; Alaide Chieffo

doi:10.1016/j.iccl.2015.12.001

Left Main Percutaneous Coronary Intervention

Interv Cardiol Clin. 2016 Apr;5(2):125-134. doi: 10.1016/j.iccl.2015.12.001. Epub 2016 Feb 10.

Authors

Neil Ruparelia¹, Alaide Chieffo²

Affiliations

¹ Department of Interventional Cardiology San Raffaele Scientific Institute, Via Olgettina 60, Milan 20132, Italy; Department of Cardiology Imperial College, Du Cane Road, London W12 0HS, UK.
² Department of Interventional Cardiology San Raffaele Scientific Institute, Via Olgettina 60, Milan 20132, Italy. Electronic address: alaide.chieffo@hsr.it.

PMID: 28582198
DOI: 10.1016/j.iccl.2015.12.001

Abstract

Significant unprotected left main stem (ULMS) disease is in approximately 5% to 7% of patients undergoing coronary angiography. Historically, coronary artery bypass grafting has been the gold standard treatment of these patients. With recent advances in stent technology, adjunctive pharmacotherapy, and operator experience, percutaneous coronary intervention (PCI) is increasingly regarded as a viable alternative treatment option, especially in patients with favorable coronary anatomy (low and intermediate SYNTAX (Synergy Between Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery) scores). This article aims to discuss the evidence supporting PCI for ULMS disease, current guidelines, and technical aspects.

Keywords: Coronary artery bypass grafting; Drug-eluting stents; Guidelines; Heart team; Intravascular imaging; Left main stem; Percutaneous coronary intervention.

Publication types

Review

MeSH terms

Coronary Artery Disease / surgery*
Drug-Eluting Stents
Humans
Percutaneous Coronary Intervention / methods*
Practice Guidelines as Topic*
Treatment Outcome