Sarcoid-like cutaneous lesions in chronic adult paracoccidioidomycosis: report of two cases

Rev Inst Med Trop Sao Paulo. 2017 Jun 1:59:e36. doi: 10.1590/S1678-9946201759036.

Abstract

This study reports two cases of chronic paracoccidioidomycosis with sarcoid-like cutaneous lesions. The patients began the treatment in 2013 at Hospital Universitário Clementino Fraga Filho (HUCFF) of the Universidade Federal do Rio de Janeiro (UFRJ). The first case (mild form) was treated with trimethoprim-sulfamethoxazole (8 mg /kg per day, orally) for three months and, then, with half the dose for nine months; the second (moderate form), with itraconazole (200 mg per day, orally) for 12 months. We point out the rareness of the sarcoid-like cutaneous lesions and the differential diagnoses for other granulomatous diseases.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Chronic Disease
  • Humans
  • Itraconazole / therapeutic use
  • Male
  • Middle Aged
  • Paracoccidioidomycosis / complications*
  • Paracoccidioidomycosis / drug therapy
  • Paracoccidioidomycosis / pathology
  • Sarcoidosis / complications*
  • Sarcoidosis / pathology
  • Severity of Illness Index
  • Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use

Substances

  • Antifungal Agents
  • Itraconazole
  • Trimethoprim, Sulfamethoxazole Drug Combination