An Open-Label Dose-Finding Study of Allopurinol to Target Defined Reduction in Urate Levels in Hemodialysis Patients

J Clin Pharmacol. 2017 Nov;57(11):1409-1414. doi: 10.1002/jcph.939. Epub 2017 Jun 9.
No abstract available

Keywords: allopurinol; clinical trial; dosing; hemodialysis; urate.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Allopurinol / administration & dosage*
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Enzyme Inhibitors / administration & dosage
  • Female
  • Gout Suppressants / administration & dosage
  • Humans
  • Kidney Failure, Chronic / blood*
  • Kidney Failure, Chronic / drug therapy
  • Kidney Failure, Chronic / therapy*
  • Male
  • Middle Aged
  • Renal Dialysis / methods*
  • Treatment Outcome
  • Uric Acid / blood*

Substances

  • Enzyme Inhibitors
  • Gout Suppressants
  • Uric Acid
  • Allopurinol