Integrative taxonomy of Goezia spinulosa (Nematoda: Raphidascarididae) from arapaimas in the northwestern Brazil

Vet Parasitol. 2017 Aug 15:242:14-21. doi: 10.1016/j.vetpar.2017.05.011. Epub 2017 May 21.

Abstract

Arapaima gigas, a fish with a high market value, has been farmed in different localities within Brazil. Among its parasites, adults of Goezia spinulosa are reported to cause ulcers in the stomach and to result in the death of farmed fingerlings. Due to the veterinary importance of this nematode in cultured arapaimas, an integrative taxonomic study is proposed, combining morphological, ultrastructural and genetic profiles of this parasite. The fish were obtained from semi-intensive fish farming in Acre State, Brazil. The fish measured 7-42cm in total length and the intensity of infection was 1-60 parasites per fish. The site of infection was mainly the stomach. Morphological and ultrastructural analyses of G. spinulosa showed the importance of its spiny body in firmly attaching the worm to the gastric mucosa, resulting in lesions, ulcers and deep gastric perforations of the stomach wall. New sequences for partial 18S rDNA, ITS1, 5.8S and ITS2 rDNA, partial 28S rDNA, cox1 mtDNA and for cox2 mtDNA are presented. Phylogenetic reconstructions based on the partial 18S and 28S rDNA shows species of Goezia occur in a clade well separated from other genera in both analyses. Both the partial 18S and 28S rDNA genes represented good genetic markers for distinguishing genera of the Raphidascarididae, with exception of Hysterothylacium. This integrated taxonomic study produced a robust profile for G. spinulosa that will aid the diagnosis of both adults and larval stages from arapaimas and possible intermediate hosts.

Keywords: 18S rDNA; 28S rDNA; Arapaima gigas; Brazil; ITS1 5.8S and ITS2; Nematoda; Scanning electron microscopy; cox1 mtDNA; cox2 mtDNA.

MeSH terms

  • Animals
  • Brazil / epidemiology
  • DNA, Helminth / genetics
  • Female
  • Fish Diseases / epidemiology
  • Fish Diseases / parasitology*
  • Fishes
  • Male
  • Nematoda / classification*
  • Nematoda / genetics
  • Nematoda / ultrastructure
  • Nematode Infections / epidemiology
  • Nematode Infections / parasitology
  • Nematode Infections / veterinary*
  • Phylogeny
  • RNA, Helminth / genetics
  • RNA, Ribosomal, 18S / genetics
  • RNA, Ribosomal, 28S / genetics

Substances

  • DNA, Helminth
  • RNA, Helminth
  • RNA, Ribosomal, 18S
  • RNA, Ribosomal, 28S